Hepatitis C Genotyping is a specialized molecular test used to identify the genotype and subtype of Hepatitis C Virus (HCV) in patients with confirmed HCV RNA positivity. This test helps determine the specific HCV genotype (1–6) and commonly differentiates subtype 1a and 1b, which is important for treatment planning, antiviral drug selection, resistance evaluation, and clinical management of chronic hepatitis C infection. The assay is generally performed using RT-PCR amplification followed by Sanger sequencing or hybridization-based molecular methods on serum or plasma samples. According to Labcorp, this test is intended for genotyping of the six major HCV types and subtyping for HCV 1a and 1b, while Mayo Clinic notes that the test is useful before initiating antiviral therapy in chronic HCV infection. Genotyping may not be successful if the viral load is low, and many reference labs require a minimum HCV viral load threshold before performing the test.
Fasting
Not Required
Reporting Time
4–6 Days
Gender
Male/Female
Age Group
All Age Group
✔ Home collection available ✔ No hidden charges
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