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EGFR Mutation Analysis (MB0101)

Description

EGFR Mutation Analysis is a molecular diagnostic test used to detect mutations in the Epidermal Growth Factor Receptor (EGFR) gene, most commonly in non-small cell lung cancer (NSCLC). This test helps identify clinically significant mutations in exons 18, 19, 20, and 21 of the EGFR gene that may predict response or resistance to EGFR tyrosine kinase inhibitor (TKI) targeted therapy such as erlotinib, gefitinib, afatinib, osimertinib, and other targeted agents. EGFR mutation testing is commonly performed on tumor tissue or cytology specimens and is essential for personalized cancer treatment planning, prognosis assessment, and therapy selection in patients with suspected or confirmed lung adenocarcinoma or advanced NSCLC. It is an important precision oncology test that guides oncologists in selecting the most effective targeted treatment strategy.

Report Time

Fasting

Not Required

Reporting Time

7–10 Days

Gender

Male/Female

Age Group

All Age Group

Pre-Test Instructions:

  • No fasting required
    Test is generally ordered for suspected or confirmed NSCLC (especially adenocarcinoma subtype)
    Submit pathology report with specimen for proper interpretation and adequacy review
    Preferred specimen is FFPE tumor tissue block or unstained slides with H&E slide
    Ensure adequate tumor content in specimen for reliable molecular analysis
    Avoid poorly preserved, insufficient, heavily fixed, or damaged tissue
    A negative result does not completely exclude EGFR mutation, especially if mutation is below assay detection limit or outside tested regions
    Common clinically relevant mutations are in exons 18, 19, 20, and 21
    Some mutations indicate sensitivity to EGFR-targeted therapy, while others (such as T790M or some exon 20 insertions) may indicate resistance to certain EGFR TKIs

Parameters Covered

रु 12,000

✔ Home collection available ✔ No hidden charges

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