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DHT (Dihydrotestosterone) (IO0056)

Description

DHT (Dihydrotestosterone) is a specialized androgen hormone test used to measure the level of dihydrotestosterone in blood, a potent metabolite of testosterone formed by the action of the enzyme 5-alpha reductase. DHT plays a major role in male sexual development, androgen-related hair loss, hirsutism, disorders of sexual differentiation (DSD), 5-alpha reductase deficiency, and monitoring of 5-alpha reductase inhibitor therapy such as finasteride or dutasteride. This test is useful in the evaluation of androgen excess, male pattern baldness, female alopecia, hormonal imbalance, virilization, and selected endocrine or reproductive disorders. Labcorp notes that DHT testing may be used in the differential diagnosis of diseases of sexual differentiation, where DHT may be low compared to testosterone in 5-alpha reductase deficiency, and it may also be used to monitor the effectiveness of 5-alpha reductase inhibitor treatment in female alopecia. The test is typically performed on serum or plasma using highly sensitive HPLC-MS/MS / LC-MS/MS methodology, with results generally reported in ng/dL.

Report Time

Fasting

Not Required

Reporting Time

7–10 Days

Gender

Male/Female

Age Group

5-99 yrs.

Pre-Test Instructions:

  • No fasting required
    Morning sample may be preferred for better endocrine correlation (recommended in hormone workups)
    Serum is preferred specimen
    Separate serum/plasma from cells within 1 hour of collection
    Transfer to plastic transport tube before freezing
    Store and transport frozen whenever possible
    Avoid grossly hemolyzed, lipemic, or poor-quality samples
    Clinical correlation with Total Testosteron

Parameters Covered

रु 5,200

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